About the Tri-State Trek

Just wanted to send a note to say how amazing the Tri-State Trek was. This fight is so important. I love everything about the event: the riders, the volunteers (I seriously dream about your Bella's chili), Mary Lou's cheering squad and riders, the HILLS, the beautiful scenery... I can't think of a better way to find a cure for ALS.

Shannon McLaughlin
Tri-State Trek Rider
Team Capt: Matty's Spinsters

The ALS TDI Tri-State Trek raises money and brings attention to the work ALS TDI is doing to find an effective treatment for a horrific disease.

The Trek began in 2003, when 16 cyclists pedaled from Boston to New York and raised about $30k for ALS research. The event has since grown to 300 participants, raising over 3 million dollars. People ride to see changes in medical science, and the spectators who cheer them on with cowbells let them know they're not alone on their bikes.

We Need More Cowbell!

In 2005, in an effort to bolster spectator support, Interns for the Trek passed out cowbells in White Plains, NY, (the Trek's former finish line) as part of a community outreach project. In 2006, the event officially launched its 'More Cowbell!' campaign; a knock-off on the pop-culture catch phrase originally delivered by Christopher Walken in a quasi-famous Saturday Night Live skit. Cowbells have been used in cycling since the early 1900s, when European's would cheer riders racing through the Pyrenees or up the Italian Alps.

For the cyclists, volunteers, and countless spectators and supporters, "More Cowbell!" is about more noise and more support for an orphaned disease and its patients that will not stand silent.

About the ALS Therapy Development Institute (ALS TDI)

The ALS Therapy Development Institute (ALS TDI) is the world's leading ALS research organization and aims to discover and develop effective treatments and a cure for ALS. Built by and for patients, the Cambridge, MA based drug development institute operates as a 501(c)(3) non-profit: combining the optimal entrepreneurial practices of a biotechnology and pharmaceutical company with the passion and urgency of a nonprofit mission. For more information, please visit us online at www.als.net.

About ALS

Amyotrophic lateral sclerosis (ALS, Lou Gehrig's disease) is a progressive neurodegenerative disease that leads to paralysis, due to the death of motor neurons in the spinal cord and brain. There is no known cause, cure, or effective treatment for the disease. Patients become trapped in their bodies, unable to speak, eat, or breathe on their own. Most succumb to respiratory failure within three to five years of diagnosis.

Approximately 5,000 US citizens are diagnosed with ALS each year, and another 5,000 die, leaving only about 30,000 patients in the United States today and an estimated 400,000 worldwide at any one time.